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Yunzhi mushroom

Coriolus versicolor, also known as Bolet à Couleurs Variées, Bolet Versicolore, Boletus versicolor, Champignon Coriolus, Champignon de Queue de Dinde, Coriolus, C. versicolor, Hongo Coriolus, Kawaratake, Krestin, Polypore à Couleurs Variées, Polypore Versicolor, Polyporus Versicolor, Polysaccharide-K, Polysaccharide Krestin, Polysaccharide Peptide, Polysaccharopeptide, Polystictus versicolor, PSK, PSP, VPS, Trametes versicolor, T. versicolor, Turkey Tail, Yun Zhi, Yun-Zhi, 云芝, 雲芝, is a mushroom of the Basidiomycetes class.

It was first used in China as a tonic dating back to the Ming Dynasty, in the 1300s, but recent studies suggest that it has immunestimulating and many other beneficial properties. It appears to work as a Biological Response Modifier, enhancing the body’s own use of macrophages and T-lymphocytes, rather than directly attacking any undesired elements in the body. Polysaccharide-K (PSK) and Polysaccharidepeptide (PSP), are protein-bound polysaccharides derived from Coriolus versicolor, which was developed after centuries of collective research in Japan and China. Since its discovery, there have been hundreds of scientific and clinical studies published demonstrating the potential benefits of the Coriolus versicolor.

Coriolus versicolor is one of the most widely studied supplements for it’s immune building properties. It is good for all people including the elderly, the physically weak, those who are overworked and those who are undergoing chemotherapy or radiation therapy. There have been over 500 human studies world wide including over a dozen human based, randomized, doubleblinded controlled clinical, placebo trials and more than 400 scientific papers that have been published world wide regarding this amazing product. In a Queensland University of Technology research report, Coriolus versicolor has been found to be 100 percent effective in suppressing prostate tumor development in mice during early trials, new research shows.

MD Anderson Cancer Institute, the University of Texas states that PSP is a: “promising candidate for chemoprevention due to the multiple effects on the malignant process, limited side effects and safety of daily oral doses for extended periods of time.” Sloan Kettering Cancer Institute of NY reported that the polysaccharopeptide of Coriolus versicolor appeared to improve survival rates in patients with gastric and colorectal cancers when used as an adjuvant.

Hartford Hospital, Connecticut reports, “It is thought that Coriolus extracts work by stimulating the body’s own cancerfighting cells. PSK and PSP may also have cancer-preventive effects.” The School of Pharmacy, University of Hong Kong states, ….The CV extract is likely to be valuable for the treatment of some forms of human leukemia.” Loma Linda University: reports: “These results indicate that IL-2 and PSP can slow progression of H238 tumors and that the mechanisms of action may be related to their direct cytotoxic effects, as well to their immunomodulatory properties.”

The results of a very important year long clinical trial examining the effects of mushroom supplementation in patients with Human Papillomavirus (HPV) were so impressive they were presented in 2008 at the 20th European Congress of Obstetrics and Gynocology. Dr. Silva Couto and his research team found that Coriolus versicolor supplementation over the period of one year substantially increased regression of dysplasia and induced clearance of the high-risk subtypes of the HPV responsible for cervical cancer. Coriolus supplementation demonstrated a 72 percent regression rate in lesions compared to 47.5 percent without supplementation, and a 90 percent regression rate in the high risk HPV virus sub-types compared to 8.5 percent without.

We believe the best place to buy Yunzhi as a dietary supplement is Mushroom Remedy.

medical doctor

According to the results of these clinical and research studies, Coriolus versicolor may be used to improve your health from the following conditions:

  • Autoimmune Disease
  • Bronchitis
  • Colitis
  • Herpes
  • Human Papillomavirus (HPV)
  • Leukemia
  • Cancer treatment
    • Prostate Cancer
    • Breast Cancer
    • Bronchogenic Carcinoma
    • Cervical Cancer
    • Colon Cancer
    • Colorectal Cancer
    • Esophageal Cancer
    • Gastric Cancer
    • Primary Hepatocellular Carcinoma
    • Liver Cancer
    • Lung Cancer
    • Nasopharyngeal cancer
    • Oesophageal Cancer
  • Chronic Fatigue Syndrome
  • Diabetes
  • Fibromyalgia
  • Hepatitis
  • High Blood Pressure
  • High-grade Squamous Intraepithelial lesion (HSIL)
  • HIV Virus
  • Inflammatory
  • Infections – include:
    • Skin infections, including impetigo
    • Urinary tract infections
    • Digestive tract infections
  • Lung disorders
  • Lymphoma
  • Melanoma
  • Non-Hodgkin Lymphoma (NHL)
  • Poor appetite
  • Primary Biliary Cirrhosis (PBC)
  • Ringworm
  • Scleroderma
  • Septic shock
  • Tumor
  • Ulcerative Colitis
  • Allergy
  • Asthma

Other Coriolus versicolor benefits:

  • Immunomodulator
  • Immunostimulation
  • Boosting the immune system
  • Increase strength and stamina
  • Cancer prevention
  • Reduce chemotherapy side effects
  • Reduce Radiation therapy side effects

Potential Side effects of Coriolus versicolor:

  • In very rare cases – passage of dark colored stools or darkening of fingernails
  • No other known reported side effects

mushroom vendor

Coriolus versicolor References:

Science Daily:

Natural News:

Medical News Today:

U.S. National Library of Medicine:

Sloan Kettering Cancer Institute:


Best Place to Buy Yunzhi or Coriolus versicolor:

Mushroom Remedy:



Immunomodulatory and antitumor properties of polysaccharide peptide (PSP)

Piotrowski J, Jędrzejewski T, Kozak W Abstract Modern medicine successfully uses multiple immunomodulators of natural origin, that can affect biological reactions and support body’s natural […]

Posted in Appetite, Cancer, Chemotherapy, Fatigue, Immune, Tumor, Yunzhi | Tagged , , , , , , , , , , , , , , , | Leave a comment

Modulation of antipyrine clearance by polysaccharide peptide (PSP) isolated from Coriolus versicolor in the rat

Chan SL, Yeung JH Abstract Polysaccharide peptide (PSP), isolated from Coriolus versicolor COV-1, has been previously shown to have immuno-stimulatory, anti-tumour and analgesic effects in […]

Posted in Appetite, Cancer, Chemotherapy, Clinical trial, Immune, Tumor, Yunzhi | Tagged , , , , , , , , , | Leave a comment

Restoration of immunologic responsiveness by PSK in tumor-bearing animals

Matsunaga K, Morita I, Oguchi Y, Fujii T, Yoshikumi C, Nomoto K Abstract PSK is a protein-bound polysaccharide prepared from cultured mycelium of the Basidiomycete […]

Posted in bladder cancer, Fibrosarcomas, Immune, liver cancer, lung cancer, Melanoma, Sarcoma, Tumor, Yunzhi | Tagged , , , , , , , , , , , , , , , , , , , , | Leave a comment

Anti-tumor effect of Coriolus versicolor methanol extract against mouse B16 melanoma cells: In vitro and in vivo study

Harhaji Lj, Mijatović S, Maksimović-Ivanić D, Stojanović I, Momcilović M, Maksimović V, Tufegdzić S, Marjanović Z, Mostarica-Stojković M, Vucinić Z, Stosić-Grujicić S Abstract Numerous studies […]

Posted in Immune, Melanoma, Tumor, Yunzhi | Tagged , , , , , , | Leave a comment

In vitro immunomodulating effect of protein-bound polysaccharide, PSK on peripheral blood, regional nodes, and spleen lymphocytes in patients with gastric cancer

Nio Y, Shiraishi T, Tsubono M, Morimoto H, Tseng CC, Imai S, Tobe T Abstract PSK, a protein-bound polysaccharide, has been widely used for cancer […]

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The Antibacterial Activity of Coriolus versicolor Methanol Extract and Its Effect on Ultrastructural Changes of Staphylococcus aureus and Salmonella Enteritidis

Danka Matijašević, Milena Pantić, Božidar Rašković, Vladimir Pavlović, Dunja Duvnjak, Aleksandra Sknepnek, Miomir Nikšić Abstract The antibacterial activity of methanol extract obtained from fruiting body […]

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Protein-bound polysaccharides from Coriolus versicolor attenuate LPS-induced synthesis of pro-inflammatory cytokines and stimulate PBMCs proliferation

Jędrzejewski T, Pawlikowska M, Piotrowski J, Kozak W Abstract Protein-bound polysaccharides (PBP) isolated from Coriolus versicolor (CV) are classified as biological response modifiers capable of […]

Posted in Immune, Infection, Tumor, Yunzhi | Tagged , , , , , , , , , , , , , , | Leave a comment

Polysaccharopeptide from the Turkey Tail Fungus Trametes versicolor (L.:Fr.) Pilát Inhibits Human Immunodeficiency Virus Type 1 Reverse Transciptase and Protease

Tzi Bun Ng, Hexiang Wang, D. C. C. Wan ABSTRACT Polysaccharopeptide from the Turkey Tail fungus Trametes (=Coriolus) versicolor has been reported to possess a […]

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Polysaccharopeptide from Coriolus versicolor has potential for use against human immunodeficiency virus type 1 infection

Collins RA, Ng TB Abstract Polysaccharopeptide (PSP) isolated from the edible mushroom Coriolus versicolor was tested for its potential as an anti-human immunodeficiency virus type […]

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Immunopharmacologic agents in the amelioration of hepatic injuries

Farghali H, Masek K Abstract A number of immunomodulating agents of different origin have been shown to reduce liver injury of various etiologies. Immunostimulants like […]

Posted in Hepatitis, Immune, Liver, Yunzhi | Tagged , , , , , , , , , , , , , , | Leave a comment